Award details

The role of NPR1 in glutathione-mediated communication between pathogen resistance and excess light acclimation pathways in Arabidopsis

ReferenceP18073
Principal Investigator / Supervisor Professor Andrew Maule
Co-Investigators /
Co-Supervisors
Institution John Innes Centre
DepartmentMetabolic Biology
Funding typeResearch
Value (£) 195,452
StatusCompleted
TypeResearch Grant
Start date 01/08/2003
End date 31/07/2006
Duration36 months

Abstract

Plants must coordinate gene expression in response to multiple stresses such as pathogen infection and exposure to excess light (EL). In the absence of salicylic acid (SA) signalling, NPR1, a key component of the SA pathway, suppresses foliar glutathione levels. This in turn determines how well leaves acclimate to EL. When SA signalling is activated, NPR1 suppression of glutathione level ceases. This inhibits acclimation making SA-induced leaves more sensitive to EL. Thus glutathione and NPR1 can mediate communication between pathogen resistance- and EL acclimation- pathways. This proposal will: 1) investigate the extent of glutathione-mediated regulation of the leaf transcriptome in response to combined stresses; 2) determine how NRP1-interacting proteins control glutathione levels; and 3) determine how glutathione can influence one or more signalling pathways.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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