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Transcriptional regulation of phenylpropanoid biosynthesis in legumes

ReferenceP17923
Principal Investigator / Supervisor Professor Trevor Wang
Co-Investigators /
Co-Supervisors
Professor Cathie Martin
Institution John Innes Centre
DepartmentMetabolic Biology
Funding typeResearch
Value (£) 171,096
StatusCompleted
TypeResearch Grant
Start date 01/03/2003
End date 31/08/2006
Duration42 months

Abstract

The phenylpropanoid pathway in plants gives rise to many bioactive secondary metabolites that are important in plant defence, plant symbiosis, human and animal health and nutrition. We intend to use functional genomics coupled to data mining to discover transcriptional regulators of the phenylpropanoid biosynthetic pathway in the model legume, Lotus japonicus. In addition to tannins and anthocyanins, legumes produce important therapeutic compounds, isoflavonoids, so that three possible routes for the elaboration of flavanone intermediates can be examined to provide knowledge of the control of pathway flux. These discoveries will facilitate beneficial manipulation of the pathway and its activation in other organisms for molecular pharming. (Joint with grant 17925).

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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