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Investigating the molecular basis of appressorium- mediated plant infection by Magnaporthe grisea
Reference
P17477
Principal Investigator / Supervisor
Professor Nicholas Talbot
Co-Investigators /
Co-Supervisors
Institution
University of Exeter
Department
Biosciences
Funding type
Research
Value (£)
232,060
Status
Completed
Type
Research Grant
Start date
09/09/2002
End date
09/09/2005
Duration
36 months
Abstract
The importance of lipid metabolism to appressorium turgor generation by the rice blast fungus Magnaporthe grisea will be investigated. The VTL1 vacuolar triacylglycerol lipase gene will be characterised by targeted gene replacement. Triacylglycerol lipase(s) will be purified from developing appressoria and characterised. The potential role of peroxisomal- beta-oxidation and the glyoxylate pathway in appressorium turgor generation will be assessed by characterisation of the non-pathogenic pth2 mutant, which lacks carnitine acyl transferase. Mutational analysis of the KAT1 and PHE1 genes which encode beta-oxidation enzymes, and the ICL1 isocitrate lyase gene will be carried out to test the hypothesis that glycerol accumulation in appressoria results predominantly from rapid vacuolar degradation of lipid bodies.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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