Award details

Molecular and physiological characterisation of a hormone response mutant

ReferenceP17270
Principal Investigator / Supervisor Dr Stephen Jackson
Co-Investigators /
Co-Supervisors
Institution University of Warwick
DepartmentWarwick HRI
Funding typeResearch
Value (£) 157,396
StatusCompleted
TypeResearch Grant
Start date 06/01/2003
End date 05/11/2006
Duration46 months

Abstract

A T-DNA tagged Arabidopsis mutant has been isolated that has reduced stature and altered response to ABA and brassinosteroid in germination assays. The T-DNA has inserted in a novel plant gene which in database searches shows highest homology to mammalian and fruit-fly heparin sulphate polymerases involved in the production of heparin sulphate proteoglycans (HSPGs). Membrane bound HSPGs are proposed to act as co-receptors and or internalisation receptors, and have not been described in plants before. We intend to characterise the mutant further, establish whether it is disrupted in heparin sulphate polymerase activity, and investigate the role of heparin sulphate and HSPGs in plant development.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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