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Plant cylic nucleotide-gated channels; an electrophysiological characterisation
Reference
P17243
Principal Investigator / Supervisor
Professor Dale Sanders
Co-Investigators /
Co-Supervisors
Professor Frans Maathuis
Institution
University of York
Department
Biology
Funding type
Research
Value (£)
180,740
Status
Completed
Type
Research Grant
Start date
01/06/2002
End date
31/05/2005
Duration
36 months
Abstract
Cyclic nucleotide-gated channels (CNGCs) are widely distributed in plants and function in signal transduction and ion uptake. Molecular studies are revealing information on expression, and mutants are generating physiological information, but very little is known concerning the underlying properties of CNGCs. The ion permeation and gating characteristics of selected CNGC isoforms from Arabidopsis will be determined in heterologous expression systems (especially HEK cells). The contribution of CNGCs to membrane transport in planta will be established (in studies employing both conventional impalement and patch clamp electrophysiology) by comparison of wild type plants with CNGC knock-out mutants and lines silenced for several CNGCs using dsRNAi.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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