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The physiology and biochemistry of bacterial selenate respiration

Reference	P17219
Principal Investigator / Supervisor	Dr Clive Butler
Co-Investigators / Co-Supervisors	Professor David Richardson
Institution	Newcastle University
Department	Inst for Cell and Molecular Biosciences
Funding type	Research
Value (£)	94,764
Status	Completed
Type	Research Grant
Start date	01/10/2002
End date	01/11/2003
Duration	13 months

Abstract

Bacterial selenate reduction contributes significantly to the global selenium cycle and is the major process responsible for the reduction of selenate to insoluble elemental Selenium. Two biochemically distinct selenate reductases have been isolated and preliminary data suggest that selenate reduction is catalysed at an active site molybdenum cofactor. In the present work, selenate reduction in both Aeromonas hydrophila and Enterobacter cloacae SLD1a-1 will be studied. Using a combination of whole cell physiology, molecular biology, biochemistry and spectroscopy we will investigate the microbial bioenergetics of selenate respiration and the biochemical diversity of the bacterial selenate reductase systems.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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