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The role of Ca2+ -pumps in Ca2+ -homeostasis and signalling

Reference	P17217
Principal Investigator / Supervisor	Dr Lorraine Williams
Co-Investigators / Co-Supervisors
Institution	University of Southampton
Department	Centre for Biological Sciences
Funding type	Research
Value (£)	195,128
Status	Completed
Type	Research Grant
Start date	01/10/2002
End date	31/03/2006
Duration	42 months

Abstract

A small family of type IIA Ca2+ -ATPases (AtECA1-3) has recently been identified in Arabidopsis. This proposal will use molecular and biochemical techniques to address the functional significance of two of these Ca2+ -pumps (AtECA2 and 3) in Ca2+ -homeostasis and signalling. Physiological function will be addressed by analysing the phenotype of knockout mutants and transgenic plants in which these genes are over-expressed. The in vivo effect of altering Ca-pump expression levels on cytosolic free calcium concentrations in response to stress will be monitored by crossing these plants into aequorin-expressing lines.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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