BBSRC Portfolio Analyser
Award details
Understanding specificity in plant cell signal transduction through an analysis of protein complex formation
Reference
P17154
Principal Investigator / Supervisor
Dr Michael Roberts
Co-Investigators /
Co-Supervisors
Institution
Lancaster University
Department
Biological Sciences
Funding type
Research
Value (£)
194,056
Status
Completed
Type
Research Grant
Start date
09/09/2002
End date
09/09/2005
Duration
36 months
Abstract
A major current objective of research into cell signalling is the discovery of mechanisms for maintaining specificity within pathways which often include shared components. One mechanism to achieve specificity is to physically link relevant protein molecules together in distinct functional complexes. The work described in this application aims to examine the role of scaffolding proteins which perform this function in Arabidopsis. Primarily, we will focus on an existing example involved in the ethylene signalling pathway, namely the interaction of CTR1 kinase and 14-3-3 proteins. Subsequently, we will expand the work to investigate more wide-ranging examples of complex formation involving protein kinases. The project aims to exploit information from the Arabidopsis genome sequence to marry molecular genetic and biochemical approaches.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search