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Genetic and mechanistic approaches to understanding the Tat protein translocase

ReferenceP16795
Principal Investigator / Supervisor Professor Benjamin Berks
Co-Investigators /
Co-Supervisors
Professor Tracy Palmer
Institution University of Oxford
DepartmentBiochemistry
Funding typeResearch
Value (£) 326,804
StatusCompleted
TypeResearch Grant
Start date 05/06/2002
End date 04/12/2005
Duration42 months

Abstract

The Tat system is a recently-discovered bacterial protein export pathway that possesses the remarkable ability of transporting folded polypeptides across the cytoplasmic membrane. Building on our initial success in characterising the Tat system of Escherichia coli we aim to further our molecular understanding of the Tat transporter by (i) genetic analysis, including the use of powerful new genetic selections, and (ii) combined biochemical-genetic approaches to mechanism.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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