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Cloning of avirulence genes from the oomycete plant pathogens Peronospora parasitica and Phytophthora infestans
Reference
P16778
Principal Investigator / Supervisor
Professor James Beynon
Co-Investigators /
Co-Supervisors
Institution
University of Warwick
Department
Warwick HRI
Funding type
Research
Value (£)
169,760
Status
Completed
Type
Research Grant
Start date
17/06/2002
End date
17/06/2005
Duration
36 months
Abstract
Peronospora parasitica and Phytophthora infestans are model pathogens for studying plant host-oomycete interactions. Using map-based cloning, we will isolate pathogen avirulence genes, products of which interact with the products of corresponding resistance genes in the hosts, respectively, Arabidopsis and potato. Proof that avirulence genes have been cloned will be gained by either direct complementation of virulent pathogen races, heterologous expression in related oomycetes, or transient expression in planta. Avirulence genes, and genes closed linked to them, will be used as probes to seek homologues in the other oomycete. Common sequences will be investigated in P. infestans for a role in either pathogenicity or avirulence by overexpression or gene silencing.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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