Award details

Suppression of programmed cell death in Arabidopsis

Reference	P16645
Principal Investigator / Supervisor	Dr Patrick Gallois
Co-Investigators / Co-Supervisors	Professor Simon Turner
Institution	The University of Manchester
Department	Life Sciences
Funding type	Research
Value (£)	223,280
Status	Completed
Type	Research Grant
Start date	01/05/2002
End date	31/10/2005
Duration	42 months

Abstract

We have set up a protoplast system in Arabidopsis where Programmed Cell Death (PCD) can be induced in a consistent and synchronous manner. This allowed us to identify a protein able to suppress PCD. This protein is homologous to DAD1, a mammalian protein that interacts with a regulator of cell death. We propose i) to characterise the mechanism by which AtDAD1 suppresses PCD in plants, ii) to identify proteins interacting with AtDAD1 iii) to carry out an activation tagging screen for PCD suppressors. This will provide a much-needed insight into plant PCD, providing new gene sequences and the possibility of novel mutant screens.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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