BBSRC Portfolio Analyser
Award details
Role of the Rcs two-component pathway in bacterial growth on solid surfaces and biofilm formation
Reference
P16371
Principal Investigator / Supervisor
Dr David Clarke
Co-Investigators /
Co-Supervisors
Institution
University of Bath
Department
Biology and Biochemistry
Funding type
Research
Value (£)
192,500
Status
Completed
Type
Research Grant
Start date
01/07/2002
End date
01/07/2005
Duration
36 months
Abstract
Despite the economic importance of biofilms remarkably little is known about how bacteria regulate gene expression during the formation of these surface-associated communities. Recent results suggest that the Rcs two-component pathway in Escherichia coli may play a regulatory role. The objective of this study is, therefore, to characterise the role of the Rcs two-component pathway in regulating the changes in gene expression associated with the transition from planktonic growth to growth on a solid surface. This objective will be achieved by: 1) genetic and biochemical characterisation of the Rcs two-component pathway and 2) identification of the genes controlled by this pathway and genetic analysis of their role in biofilm formation.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search