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Polyunsaturated fatty acid biosynthesis: functional characterisation of novel elongase components

Reference	P16340
Principal Investigator / Supervisor	Professor Johnathan Napier
Co-Investigators / Co-Supervisors
Institution	Rothamsted Research
Department	Plant Biology & Crop Science
Funding type	Research
Value (£)	164,704
Status	Completed
Type	Research Grant
Start date	01/04/2003
End date	31/03/2006
Duration	36 months

Abstract

We have genetically identified two novel Arabidopsis cDNAs as encoding functional components of the microsomal fatty acid elongase, responsible for the synthesis of very long chain fatty acids. The potential to use these elongase components to enhance synthesis of these important components (of glycerolipids, waxes and ceramides) will be investigated by transcriptional modulation in transgenic plants. In particular, the activity of a heterologous elongating activity responsible for the biosynthesis of 20 carbon polyunsaturated fatty acids will be studied. The aim of this project is to enhance our capacity to synthesise these important pharmaceutical compounds in transgenic plants.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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