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Regulation of bacterial thiosulphate oxidation

Reference	P15830
Principal Investigator / Supervisor	Professor Benjamin Berks
Co-Investigators / Co-Supervisors	Dr Corrine Appia-Ayme
Institution	University of Oxford
Department	Biochemistry
Funding type	Research
Value (£)	56,088
Status	Completed
Type	Research Grant
Start date	01/03/2002
End date	31/05/2003
Duration	15 months

Abstract

The Sox system is used by both photosynthetic and non- photosynthetic bacteria to oxidize thiosulfate and sulfide as electron donors for autotrophic growth. We have identified an eleven gene locus in Rhodovulum sulfidophilum encoding the Sox structural genes. The thiosulfate-oxidizing form of the Sox pathway is induced only when thiosulfate is available. This project will determine the transcriptional organisation of the sox locus and investigate the differential expression of the transcripts in response to the available sulfur species and carbon source. Genomic comparisons identify a conserved gene cluster, orfABCD, adjacent to Proteobacterial sox loci. A possible role of orfABCD in inorganic sulfur oxidation will be investigated.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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