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The role of RACs ROS and antioxidants in cell growth: Arabidopsis root hairs as a model system
Reference
P15790
Principal Investigator / Supervisor
Professor Nicholas Smirnoff
Co-Investigators /
Co-Supervisors
Institution
University of Exeter
Department
Biosciences
Funding type
Research
Value (£)
228,648
Status
Completed
Type
Research Grant
Start date
12/11/2001
End date
12/11/2004
Duration
36 months
Abstract
Root hairs grow from the tip. Precise localisation of the relevant proteins and very rapid wall synthesis and expansion are required. Our aim is to determine the roles of RAC (a small GTPase), hydrogen peroxide, ascorbate (AsA) and ascorbate oxidase in the growth of Arabidopsis root hairs. We will test the following hypotheses. 1. Root hair growth requires hydrogen peroxide formation via RHD2, an NADPH oxidase homologue. 2. RAC controls the localization and/or activity of RHD2 at the root hair tip. 3. Hydrogen peroxide strengthens the wall by allowing peroxidative cross-linking of polymers thereby preventing rupture of the rapidly expanding tip. Peroxide concentration is controlled by apoplastic AsA, itself controlled by ascorbate oxidase.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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