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Characterisation of a putative membrane-associated protein required for resistance to Phytophthora infestans in Nicotiana benthamiana
Reference
P15176
Principal Investigator / Supervisor
Professor Sir David Baulcombe
Co-Investigators /
Co-Supervisors
Dr Isabelle Malcuit
Institution
University of East Anglia
Department
Sainsbury Laboratory
Funding type
Research
Value (£)
191,056
Status
Completed
Type
Research Grant
Start date
01/04/2001
End date
05/10/2004
Duration
41 months
Abstract
Resistance to P. infestans in N. benthamiana is elicited by the INF1 elictin. We have recently identified a gene encoding a putative membrane-associated protein, required for INF1-mediated resistance to P. infestans in N. benthamiana, using a novel screening approach based on virus-induced gene silencing (VIGS). The aim of the proposed research project is to analyse the nature and function of this gene and assess its role in the signal transduction pathway leading to elictin sensitivity and late blight resistance. Expression of this gene in susceptible potato and tomato cultivars will be carried out to test whether components of the signal transduction pathway leading to non-host resistance in N. benthamiana are conserved in these plants.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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