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Analysis of the RPP13 allelic series of disease resistance genes in Arabidopsis
Reference
P15158
Principal Investigator / Supervisor
Professor James Beynon
Co-Investigators /
Co-Supervisors
Institution
University of Warwick
Department
Warwick HRI
Funding type
Research
Value (£)
214,172
Status
Completed
Type
Research Grant
Start date
10/09/2001
End date
09/02/2006
Duration
53 months
Abstract
The RPP13 gene from Arabidopsis is involved in recognition of several Peronospora parasitica (downy mildew) isolates. It is present as a single copy gene and allelic variants in other Arabidopsis accessions have different recognition specificities. RPP13 function is independent of the eds1 and ndr1 mutations and does not require salicylic acid and, hence, utilises a novel signal transduction pathway. Components of this pathway will be identified and cloned. The structure of the RPP13 locus represents an excellent model in which to study evolution of resistance gene function. This proposal will identify components of the novel signal transduction pathway and study the relationship between DNA and protein coding variation and function in RPP13 alleles.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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