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Functional characterisation of a family of proteins controlling plastid differentiation in Arabidopsis thaliana
Reference
P15112
Principal Investigator / Supervisor
Professor Cathie Martin
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
Cell and Develop Biology
Funding type
Research
Value (£)
167,528
Status
Completed
Type
Research Grant
Start date
01/05/2001
End date
01/05/2004
Duration
36 months
Abstract
Two genes, DAG from Antirrhinum majus and DAL1 from Arabidopsis thaliana are required for chloroplast development. There is evidence that DAG is also required for specialisation of non-photosynthetic plastid types. DAG and DAL1 belong to a family of proteins, comprising 9 members in Arabidopsis. DAG-related proteins are found only in plants, targeted to plastids. The function of four members of this family will be investigated using knock-out mutants in Arabidopsis. In addition to ultrastructural analysis of plastids, the effect of each mutation on transcription of the plastidial and nuclear genomes will be assayed using arrays and transcript mapping. Biochemical purification of transcription complexes will establish if DAG proteins play a direct role in transcription of the plastid genome.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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