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Factors affecting gene silencing in plants using tobacco rattle virus
Reference
P15101
Principal Investigator / Supervisor
Professor Sir David Baulcombe
Co-Investigators /
Co-Supervisors
Dr Ana Martin-Hernandez
Institution
University of East Anglia
Department
Sainsbury Laboratory
Funding type
Research
Value (£)
204,336
Status
Completed
Type
Research Grant
Start date
05/06/2001
End date
05/06/2004
Duration
36 months
Abstract
Tobacco rattle virus (TRV) is a more effective gene silencing vector than either PVX or TMV. We propose to investigate the basis of the gene silencing properties of TRV by analysis of strains and mutants of TRV. We shall also investigate the ability of TRV-encoded proteins to influence the outcome of gene silencing in plants. In concert with these molecular analyses we shall investigate the possibility that gene silencing is influenced by the ability of the virus to induce recovery, to invade meristems and to evade the gene silencing mechanism. These results will be exploited for developing refined, easy to use TRV-induced gene silencing in N. benthamiana and Arabidopsis.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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