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Acetate regulation of plant metabolism and development through gene expression
Reference
P14659
Principal Investigator / Supervisor
Dr Mark Hooks
Co-Investigators /
Co-Supervisors
Institution
Bangor University
Department
Sch of Biological Sciences
Funding type
Research
Value (£)
207,792
Status
Completed
Type
Research Grant
Start date
01/07/2001
End date
30/09/2004
Duration
39 months
Abstract
Acetate regulates gene expression in eukaryotic organisms. This has been unequivocally demonstrated for the fungus E. nidulans, where acetate sensitive regulators were identified. Strong experimental evidence supports a similar role for acetate in higher plants. The experimental program will test this hypothesis by characterising mutants unable to utilise or sense acetate. The extent to which altering acetate metabolism affects metabolic gene expression will be determined. Signalling mechanisms will also be explored through characterisation of apparent protein kinase and acyl-CoA synthetase mutants. An important goal is to relate developmental defects observed in the mutants to altered metabolism and gene expression.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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