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Comparative analysis of the defence proteome of the model plant Arabidopsis thaliana
Reference
P14635
Principal Investigator / Supervisor
Professor Murray Grant
Co-Investigators /
Co-Supervisors
Professor John Mansfield
Institution
Imperial College London
Department
Agricultural Sciences
Funding type
Research
Value (£)
264,000
Status
Completed
Type
Research Grant
Start date
18/06/2001
End date
17/08/2004
Duration
38 months
Abstract
In this project we will document changes in the Arabidopsis leaf proteome after challenge by avirulent, virulent and hrp mutant strains of Pseudomonas syringae pv. tomato (DC3000). Expression proteomics, utilising 2-D gel electrophoresis and mass spectroscopy following sub-cellular fractionation, will be used to establish a global picture of how components of the defence proteome change during susceptible or resistant interactions (both gene-for-gene and innate immunity). Our comparative studies will facilitate an understanding of signalling hierarchies activated or suppressed during the plants perception of an invading microbe, and allow determination of post-translational modifications not evident from traditional transcriptome approaches.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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