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Role and function of caspase-like activity in the execution of programmed cell death in plants
Reference
P14516
Principal Investigator / Supervisor
Dr Patrick Gallois
Co-Investigators /
Co-Supervisors
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
140,236
Status
Completed
Type
Research Grant
Start date
25/06/2001
End date
25/06/2003
Duration
24 months
Abstract
There are many situations in plant growth and development where self-destruction of cells is required. This includes the germination of seeds, the differentiation of tracheary elements, reproduction and senescence. The hypersensitive reaction (HR) against a pathogen attack is also relevant to cell death. Very little is known about the core mechanism of programmed cell death in plants. We have identified a key protease activity associated with plant cell death, the identification of which represents a break through. We propose to employ a combined biochemical and molecular genetic approach to i) identify and fully characterise the protease and its gene ii) to understand its role and function in the execution of cell death iii) to use this knowledge to identify additional components of the cell death machinery.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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