BBSRC Portfolio Analyser
Award details
The biochemical diversity of bacterial nitrate assimilation
Reference
P13842
Principal Investigator / Supervisor
Professor David Richardson
Co-Investigators /
Co-Supervisors
Institution
University of East Anglia
Department
Biological Sciences
Funding type
Research
Value (£)
175,536
Status
Completed
Type
Research Grant
Start date
01/10/2001
End date
01/10/2004
Duration
36 months
Abstract
Assimilatory nitrate reductases (NAS) are widely distributed in bacteria and contribute significantly to the global nitrogen cycle. Analysis of NAS amino acid sequences reveals that they may be sub-grouped into three distinct types. We will study representative examples of two types, one from the enteric bacterium Klebsiella oxytoca and the other from the cyanobacterium Synechococcus sp. PCC7942. Using biochemical, spectroscopic and physiological methods we will investigate: 1) the biology and evolution of the active site of the nitrate reductases; 2) the pathways of electron transfer to the catalytic site within the different types of NAS; 3) the nature of the electron donors that link the NAS systems with the bacteria's central metabolism; and 4) the physiological importance of possessing distinct nitrate reductases for both assimilation and denitrification pathways.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search