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Comparison of the molecular bases of pathogenicity in the model oomycetes Pe. parasitica and P. infestans through a genomics approach

Reference	P13836
Principal Investigator / Supervisor	Professor James Beynon
Co-Investigators / Co-Supervisors	Professor Paul Birch
Institution	University of Warwick
Department	Warwick HRI
Funding type	Research
Value (£)	158,876
Status	Completed
Type	Research Grant
Start date	01/02/2001
End date	01/02/2004
Duration	36 months

Abstract

Peronospora parasitica and Phytophthora infestans are being developed as model systems to study the mechanisms of oomycete biotrophy and pathogenicity. Using suppression subtractive hybridisation we will identify pathogen and plant genes up-regulated specifically during pathogen growth on host plants. Pathogen genes expressed in both interactions are likely to be important in the ability of oomycetes to grow on plants. Gene silencing in P. infestans will be used to analyse their importance in infection. Using Arabidopsis, insertion mutants in plant genes altered in expression during infection by oomycetes will be identified and the effect of the mutations on pathogenicity studied. (This is a joint project with SCRI whose part is funded by SERAD.)

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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