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Structure-function analysis of the ABC maltose transporter
Reference
P13721
Principal Investigator / Supervisor
Professor Michael Ehrmann
Co-Investigators /
Co-Supervisors
Institution
Cardiff University
Department
Cardiff University Department
Funding type
Research
Value (£)
169,420
Status
Completed
Type
Research Grant
Start date
31/10/2000
End date
15/06/2004
Duration
44 months
Abstract
Bacterial ATP binding cassette (ABC) transporters and their eukaryotic family members are involved in a variety of important house keeping and disease related functions. Although ABC transporters have been studied for over 30 years, the structure of these multidomain systems is unknown and the mechanism of transport is not understood. The widely studied ABC maltose transporter MalEFGK is used as a model to apply a combination of biochemical and genetic techniques to determine basic structural and functional properties and to address the important question of mechanism.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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