Award details

Identification of a novel class of virus resistance genes by mutagenesis and map-based cloning in pea

Reference	P13344
Principal Investigator / Supervisor	Professor Andrew Maule
Co-Investigators / Co-Supervisors	Professor Thomas Ellis, Dr Stuart Harrison
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	332,368
Status	Completed
Type	Research Grant
Start date	01/02/2001
End date	07/10/2004
Duration	44 months

Abstract

Recessive resistance to potyvirus infection occurs in a wide range of crop species. In pea, such genes are clustered and show diverse specificity. The nature of the resistance suggests these examples represent a new class of resistance genes. In this project, we will use map-based cloning to characterise one of these genes (sbm-1), which provides resistance to the pea pathogen Pea Seed- borne Mosaic Virus. The cloning strategy will be based upon a deletion mutagenesis of an F1 cross between resistant and susceptible lines and mapping methods that draw on syntenic relationships with other legumes. Understanding the factors controlling specificity for these genes has great potential to combat potyvirus infections in many crops.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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