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Malate regulation of PEP carboxylase kinase expression
Reference
P13325
Principal Investigator / Supervisor
Professor Hugh Nimmo
Co-Investigators /
Co-Supervisors
Professor Gareth Islwyn Jenkins
Institution
University of Glasgow
Department
IBLS Division of Biochemistry & Molecula
Funding type
Research
Value (£)
247,292
Status
Completed
Type
Research Grant
Start date
01/08/2000
End date
01/03/2005
Duration
55 months
Abstract
We propose that the circadian control of PEP carboxylase kinase in CAM plants is a secondary response to changes in metabolite concentrations, most likely the cytosolic malate level. We also suggest that malate may regulate the expression of the kinase in other plants. We will test these hypotheses in Arabidopsis and in the CAM plant Kalanchoe fedtschenkoi by studying transgenic plants containing promoter:reporter fusions, by examining whether kinase expression in response to perturbations is gated by the circadian clock and by manipulating the malate content of plants, seedlings or cultured cells.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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