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Positioning oscillations of cytosolic free calcium in the circadian intracellular signalling pathway

Reference	P13274
Principal Investigator / Supervisor	Professor Alex Webb
Co-Investigators / Co-Supervisors
Institution	University of Cambridge
Department	Plant Sciences
Funding type	Research
Value (£)	218,268
Status	Completed
Type	Research Grant
Start date	16/10/2000
End date	16/10/2003
Duration	36 months

Abstract

The circadian clock regulates many cellular processes in plants. The signalling pathway by which the circadian oscillator regulates these cellular processes remains unidentified. It is proposed to make novel use of GAL4 transactivation in an enhancer trap line to test the hypothesis that the calcium ion is a component of the signalling pathway by which the circadian oscillator regulates stomatal movements. The role of intracellular calcium in the circadian control of stomata will be determined by measuring oscillations in intracellular calcium in guard cells, generating novel calcium-homeostasis phenotypes and causing dysfunction of the guard cell circadian oscillator. The proposed research programme will position calcium in respect to the intracellular oscillator in the circadian signalling pathway. This is an essential step in understanding how the circadian clock regulates cellular processes in plants.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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