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Genetic analysis of saponin biosynthesis in diploid oat
Reference
P13269
Principal Investigator / Supervisor
Professor Anne Osbourn
Co-Investigators /
Co-Supervisors
Institution
University of East Anglia
Department
Sainsbury Laboratory
Funding type
Research
Value (£)
276,912
Status
Completed
Type
Research Grant
Start date
01/09/2000
End date
01/09/2003
Duration
36 months
Abstract
A collection of Avena strigosa mutants that are deficient in the ability to synthesise antimicrobial triterpenoid saponins has been generated. These mutants are compromised in their resistance to a range of fungal pathogens. At least six genes for saponin biosynthesis have been identified (Sad1- Sad6), and preliminary genetic information suggests that five of these genes may be linked. The objectives of this project are: 1) to determine whether the Sad1 gene encodes beta-amyrin cyclase, the first committed enzyme in the triterpenoid pathway, as suggested by biochemical analysis and gene expression studies; and 2) to genetically map the Sad genes in diploid oat.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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