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A molecular characterisation of peptide transport in barley

Reference	P13224
Principal Investigator / Supervisor	Dr Clifford Bray
Co-Investigators / Co-Supervisors	Dr Wanda Waterworth
Institution	The University of Manchester
Department	Life Sciences
Funding type	Research
Value (£)	229,396
Status	Completed
Type	Research Grant
Start date	01/06/2000
End date	01/06/2003
Duration	36 months

Abstract

Peptide transport plays a major role in the nitrogen nutrition of the cereal embryo during germination. An additional role in the nitrogen nutrition of the developing cereal grain has also been proposed. Our recent cloning of the barley scutellar peptide transporter (HvPTR1) now facilitates a molecular characterisation of this plant plasma membrane transporter. We propose to employ biochemical, molecular genetic and immunohistochemical approaches to enhance our fundamental knowledge of the basic properties of this peptide transporter via: 1) determination of the location, distribution and physiological significance of peptide transport during seed germination and development; 2) determination of topological and structure- function relationships using mutagenesis and expression studies; and 3) elucidation of the level and mechanism through which peptide uptake across plant plasma membranes is controlled.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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