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Award details
Genetics and biochemistry of novel sulphatases in Pseudomonas species
Reference
P13214
Principal Investigator / Supervisor
Dr Michael Kertesz
Co-Investigators /
Co-Supervisors
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
194,040
Status
Completed
Type
Research Grant
Start date
01/10/2000
End date
01/10/2003
Duration
36 months
Abstract
Sulphate esters are common components of soil sulphur and play an important role in the sulphur cycle in soil organic matter. The sulphate moiety is cleaved from these compounds by sulphatase enzymes. Little is yet known of the genetics and biochemistry of bacterial sulphatases that are expressed under sulphur-limiting conditions. In this project, we will characterise a novel sulphatase and sulphotransferase from the soil species Pseudomonas putida and Pseudomonas aeruginosa at a biochemical level, and investigate the expression and distribution of the corresponding genes. These are located in an extensive gene cluster, which also includes putative inner and outer membrane transport systems, whose expression and relevance will also be examined.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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