Award details

Genetics and biochemistry of novel sulphatases in Pseudomonas species

ReferenceP13214
Principal Investigator / Supervisor Dr Michael Kertesz
Co-Investigators /
Co-Supervisors
Institution The University of Manchester
DepartmentLife Sciences
Funding typeResearch
Value (£) 194,040
StatusCompleted
TypeResearch Grant
Start date 01/10/2000
End date 01/10/2003
Duration36 months

Abstract

Sulphate esters are common components of soil sulphur and play an important role in the sulphur cycle in soil organic matter. The sulphate moiety is cleaved from these compounds by sulphatase enzymes. Little is yet known of the genetics and biochemistry of bacterial sulphatases that are expressed under sulphur-limiting conditions. In this project, we will characterise a novel sulphatase and sulphotransferase from the soil species Pseudomonas putida and Pseudomonas aeruginosa at a biochemical level, and investigate the expression and distribution of the corresponding genes. These are located in an extensive gene cluster, which also includes putative inner and outer membrane transport systems, whose expression and relevance will also be examined.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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