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Analysis of the catalytic subunit of the higher plant cellulose synthase complex
Reference
P12846
Principal Investigator / Supervisor
Professor Simon Turner
Co-Investigators /
Co-Supervisors
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
206,960
Status
Completed
Type
Research Grant
Start date
17/07/2000
End date
16/02/2004
Duration
43 months
Abstract
We have used a mutant (irx3) of the model plant Arabidopsis to identify a cellulose synthase gene specific to the plant secondary cell wall. This gene is a member of the Csa gene family. Recently we have identified another Csa gene (irx1) that is also essential for cellulose synthesis. These genes and the availability of our (irx) mutants mean we are uniquely positioned to answer a number of fundamental questions about the mechanism of cellulose synthesis: (1) To determine whether the IRX1 and IRX3 proteins interact directly; (2) To elucidate the number of different Csa genes essential for cellulose synthesis; (3) To define which structural features distinguish IRX1 from IRX3; and (4) To determine the function of the zinc-binding LIM/Ring domain.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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