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Isolation cloning and function of protein partners to the ABA-response element Nt-Syr1
Reference
P12750
Principal Investigator / Supervisor
Professor Michael Blatt
Co-Investigators /
Co-Supervisors
Institution
University of Glasgow
Department
Environmental and Evolutionary Biology
Funding type
Research
Value (£)
189,772
Status
Completed
Type
Research Grant
Start date
01/09/2000
End date
30/09/2006
Duration
73 months
Abstract
The syntaxin homologue, Nt-Syr1, plays a role in ABA-related signalling and ion channel control in tobacco and, like other syntaxins, appears to function in vesicle trafficking. We are able to purify 6 major protein functions that interact with the cytosolic domain of Nt-Syr1, based on affinity chromatography. These proteins are likely to complex with Nt- Syr1 in signalling and/or secretion, and their characterisation is therefore of importance to understanding Nt-Syr1 function. Funding is requested to develop the line of investigation: (1) to purify these proteins and clone the corresponding genes; (2) to characterise their interaction(s) with Nt-Syr1, and (3) to explore their function(s).
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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