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Cyclic nucleotide signalling and salinity in plants

ReferenceP12741
Principal Investigator / Supervisor Professor Frans Maathuis
Co-Investigators /
Co-Supervisors
Professor Dale Sanders
Institution University of York
DepartmentBiology
Funding typeResearch
Value (£) 141,724
StatusCompleted
TypeResearch Grant
Start date 01/04/2000
End date 01/04/2003
Duration36 months

Abstract

Plant cells contain cGMP and cAMP, signalling molecules that play crucial roles in animal, fungal and bacterial cells. Our results show that A. thaliana non-selective voltage independent ion channels (VICs) are deactivated by cAMP/cGMP, and that VICs form putative down stream targets in cyclic nucleotide based signalling pathways. Consistent with these observations and the notion that VICs may contribute significantly to plant Na+ entry, we find an increase in A. thaliana salt tolerance when exposed to membrane permeable cAMP/cGMP. We propose to characterise A. thaliana VICs in planta via a genetic and an electrophysiological approach, to characterise VIC genes in heterologous systems and to unravel the putative cyclic nucleotide based signalling pathway that is involved in plant salinity.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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