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Genetic biochemical and physiological characterisation of bacterial Fe(III) respiration
Reference
P11894
Principal Investigator / Supervisor
Professor David Richardson
Co-Investigators /
Co-Supervisors
Dr Paul Samuel Dobbin
Institution
University of East Anglia
Department
Biological Sciences
Funding type
Research
Value (£)
197,379
Status
Completed
Type
Research Grant
Start date
01/09/1999
End date
19/11/2002
Duration
39 months
Abstract
Bacterial respiratory Fe(III) reduction makes a considerable impact in a range of micro-oxic and anoxic environments. We have identified a number of c-type cytochromes in Shewanella frigidimarine that are either specifically expressed or significantly up- regulated in cells cultured with Fe(III) as the sole terminal electron acceptor present. We now aim to (i) study in detail the molecular basis for Fe(III)-responsive gene transcription in this bacterium, (ii) assess the roles of the different hemoproteins in Fe(III) respiration by construction of mutant strains and subsequent characterisation using continuous culture; and (iii) investigate a potential role for outer membrane beta-barrel proteins in respiratory Fe(III) reduction.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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