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The function of the hydrophobin gene family in Cladosporium fulvum

Reference	P11493
Principal Investigator / Supervisor	Professor Pietro Spanu
Co-Investigators / Co-Supervisors	Professor Nicholas Talbot
Institution	Imperial College London
Department	Biological Sciences
Funding type	Research
Value (£)	188,210
Status	Completed
Type	Research Grant
Start date	01/01/2000
End date	01/01/2003
Duration	36 months

Abstract

Fungal hydrophobins are cell wall proteins described in a number of filamentous fungi involved in a number of different functions related to morphogenesis, development and pathogenicity. In Cladosporium fulvum we have identified six hydrophobins, we propose here to investigate their function with particular attention to establishment of pathogenicity on tomato, its host plant. We will obtain genomic clones and create hydrophobin null mutants by gene ablation and mutants with reduced hydrophobin levels by co-suppression. Analysis of the mutants and complementation with other hydrophobins will reveal possible functions of these genes.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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