Award details

The Wbl protein family: its potential for wide-ranging insights into actinomycete biology

ReferenceP10321
Principal Investigator / Supervisor Professor Keith Chater
Co-Investigators /
Co-Supervisors
Institution John Innes Centre
DepartmentMolecular Microbiology
Funding typeResearch
Value (£) 169,170
StatusCompleted
TypeResearch Grant
Start date 11/01/1999
End date 11/02/2002
Duration37 months

Abstract

The aim of this proposal is a basic characterisation of the role of wbl genes in actinomycetes, which include many organisms of great industrial, environmental or medical importance. The wbl genes are a newly discovered family of orthologues and paralogues so far peculiar to actinomycetes (including pathogenic mycobacteria and industrially important streptomycetes). Their paradigm is whiB, a sporulation regulatory gene in Streptomyces coelicolor. An understanding of the expression of these genes and the evaluation of the structure and role of their products is expected to provide insights into unique physiological characteristics of actinomycetes, with potential benefits for industry, medicine and bioremediation.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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