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Characterising the molecular basis of cell proliferation in plants and its potential for manipulating plant growth and development

Reference	P10302
Principal Investigator / Supervisor	Professor Mark Caddick
Co-Investigators / Co-Supervisors	Professor John Doonan, Professor Arthur Tomsett
Institution	University of Liverpool
Department	Sch of Biological Sciences
Funding type	Research
Value (£)	216,656
Status	Completed
Type	Research Grant
Start date	01/11/1998
End date	01/06/2003
Duration	49 months

Abstract

Regulation of the cell cycle is fundamental to both growth and development. To characterise the genetic components that determine cell cycle regulation in plants, we aim to utilise a highly regulated gene expression system, allowing precise temporal regulation of cloned genes, such as cyclin and cyclin-dependent kinase structural genes, in both sense and antisense orientations. Their expression at defined developmental stages will be carefully monitored. Additionally, the transgenes will be combined and also introduced into developmental mutant backgrounds. The precise roles of the various genes will be established and their genetic interactions characterised. This work will allow us to determine the potential for utilising these genes as a means of manipulating both the growth and development of plants which may be of major significance in future crop development.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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