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Diffusion and membrane dynamics in cyanobacterial cells
Reference
P10085
Principal Investigator / Supervisor
Professor Conrad Mullineaux
Co-Investigators /
Co-Supervisors
Institution
University College London
Department
Genetics Evolution and Environment
Funding type
Research
Value (£)
210,430
Status
Completed
Type
Research Grant
Start date
18/01/1999
End date
18/01/2002
Duration
36 months
Abstract
We need a better understanding of cyanobacteria as physical systems, to complement the recent advances that have been made in their molecular biology. A combination of Fluorescence Recovery After Photobleaching (FRAP) and confocal microscopy will be used to investigate structure, membrane dynamics and diffusion in cyanobacteria. We will determine whether the thylakoid and plasma membranes are contiguous, and rates of diffusion in the cytoplasm and between the cytoplasm and the periplasm will be measured. The diffusion of markers between adjacent cells in filaments will be monitored, to test models for signalling during heterocyst development. We will generate mutants with elongated cells that will be suitable for FRAP measurements of membrane dynamics. This will allow genetic investigation of the factors determining the mobility of thylakoid membrane components.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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