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Regulation of programmed cell death following plant senescence
Reference
P09602
Principal Investigator / Supervisor
Professor Chris Leaver
Co-Investigators /
Co-Supervisors
Institution
University of Oxford
Department
Plant Sciences
Funding type
Research
Value (£)
179,779
Status
Completed
Type
Research Grant
Start date
01/05/1998
End date
30/09/2001
Duration
40 months
Abstract
Programmed cell death is essential for the correct development of all multicellular organisms. Previously my laboratory had success studying developmental processes that occur over the course of the development of cucumber cotyledons. Recently we have applied cytological and molecular approaches to the cucumber cotyledon model system to demonstrate that the cell death that occurs following senescence displays the characteristic features of programmed cell death (PCD). We feel this stage of cotyledon development is an ideal system to study plant PCD. Suppression subtractive hybridisation, in combination with cDNA libraries prepared from selected stages of cotyledon development, will be used to isolate specific cDNAs (and eventually genes) which are up- or down-regulated during cell death. Sequence analysis, expression studies and a transgenic approach will be used to investigate the role of specific genes in controlling this key developmental process.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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