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Molecular analysis of the disease resistance mechanism in potato controlled by Rx
Reference
P09585
Principal Investigator / Supervisor
Professor Sir David Baulcombe
Co-Investigators /
Co-Supervisors
Institution
University of East Anglia
Department
Sainsbury Laboratory
Funding type
Research
Value (£)
171,182
Status
Completed
Type
Research Grant
Start date
18/05/1998
End date
17/04/2002
Duration
47 months
Abstract
The Rx-locus in potato confers extreme resistance (i.e. immunity, with a hypersensitive response) against potato virus X. Both the resistance gene and the corresponding elicitor protein from the virus have been cloned. In this study we propose to use the yeast two-hybrid system to investigate the molecular interactions that mediate the Rx resistance. Specifically we shall investigate the interaction of the coat protein with the Rx protein and/or with other host encoded proteins. We shall also identify host-encoded proteins that interact with Rx and that are required for the resistance. The ultimate aim of the project is to genetically engineer Rx-mediated resistance to operate against pathogens other than potato virus X.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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