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Studies on Erwinia amylovora in planta inducible genes with a role in the fireblight disease process
Reference
P09305
Principal Investigator / Supervisor
Professor Ian Roberts
Co-Investigators /
Co-Supervisors
Dr Julie Eastgate
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
188,517
Status
Completed
Type
Research Grant
Start date
01/05/1998
End date
01/05/2001
Duration
36 months
Abstract
The study aims to identify Erwinia amylovora genes specifically induced on entry into the host plant and will involve selecting in planta induced promoters using in vivo expression technology (IVET). IVET promoter clones will be selected using models relevant to stages in fireblight disease namely, blossom infection, growth and dissemination through cortical parenchyma and over-wintering. Identification of genes activated in plant tissue will allow us to understand the adaptive response of the invading pathogen to the different host environments. In addition, this study will permit the sequential activation of virulence genes in response to entering different host tissues to be examined. Overall, this will facilitate a greater understanding at the molecular level of bacterial/host interactions pertinent to the fireblight disease process.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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