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Studies on Erwinia amylovora in planta inducible genes with a role in the fireblight disease process

Reference	P09305
Principal Investigator / Supervisor	Professor Ian Roberts
Co-Investigators / Co-Supervisors	Dr Julie Eastgate
Institution	The University of Manchester
Department	Life Sciences
Funding type	Research
Value (£)	188,517
Status	Completed
Type	Research Grant
Start date	01/05/1998
End date	01/05/2001
Duration	36 months

Abstract

The study aims to identify Erwinia amylovora genes specifically induced on entry into the host plant and will involve selecting in planta induced promoters using in vivo expression technology (IVET). IVET promoter clones will be selected using models relevant to stages in fireblight disease namely, blossom infection, growth and dissemination through cortical parenchyma and over-wintering. Identification of genes activated in plant tissue will allow us to understand the adaptive response of the invading pathogen to the different host environments. In addition, this study will permit the sequential activation of virulence genes in response to entering different host tissues to be examined. Overall, this will facilitate a greater understanding at the molecular level of bacterial/host interactions pertinent to the fireblight disease process.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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