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Determining the molecular basis of appressorium- mediated infection by Magnaporthe grisea

Reference	P08629
Principal Investigator / Supervisor	Professor Nicholas Talbot
Co-Investigators / Co-Supervisors
Institution	University of Exeter
Department	Biosciences
Funding type	Research
Value (£)	179,814
Status	Completed
Type	Research Grant
Start date	01/05/1998
End date	30/06/2001
Duration	38 months

Abstract

Plant pathogenic fungi are unique in their ability to infect intact plant hosts. To do this they often elaborate special infection structures called appressoria. Appressoria of M. grisea have been shown to generate very high turgor pressure to penetrate the plant cuticle. We recently showed that to generate high pressure appressoria accumulate molar concentrations of glycerol which is required for plant infection. This project will investigate appressorium function by characterising genes encoding enzymes involved in glycerol biosynthesis and carbohydrate mobilisation. The project has three main aims: (1) to characterise M. grisea GPD1 encoding Glycerol-3-Phosphate Dehydrogenase; (2) to determine the role of the neutral trehalase-encoding gene TRE1 in appressorium turgor generation; (3) to determine the effect of the regulatory genes PMK1, HOG1 and CPKA on turgor generation.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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