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Biotrophy-related proteins specific to the intracellular hyphae of Colletotrichum lindemuthianum
Reference
P08466
Principal Investigator / Supervisor
Dr J Green
Co-Investigators /
Co-Supervisors
Professor Gerald Bennett
Institution
University of Birmingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
163,106
Status
Completed
Type
Research Grant
Start date
01/10/1997
End date
01/04/2001
Duration
42 months
Abstract
Using monoclonal antibodies we have identified two proteins formed in the Colletotrichum- bean interaction which may have a critical role in biotrophy. A full length cDNA for one of these proteins codes for a fungal proline-rich glycoprotein; this forms a multimeric structure at the plant-fungal interface. The second protein is located in the cytoplasm of biotrophic hyphae, and there is evidence that it is race-specific. We aim to: (i) sequence the race- specific protein; (ii) study the role of both proteins in pathogenicity, biotrophy and race- specificity, (iii) search for homologues in other Colletotrichum species and obligate biotrophic fungi and (iv) study the mechanism by which the proline-rich protein forms a multimeric structure.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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