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Functional characterisation of mutants of the PufX protein from Rhodobacter sphaeroides

ReferenceP08459
Principal Investigator / Supervisor Professor Mike Jones
Co-Investigators /
Co-Supervisors
Institution University of Sheffield
DepartmentDivision of Clinical Sciences (S)
Funding typeResearch
Value (£) 38,706
StatusCompleted
TypeResearch Grant
Start date 01/09/1997
End date 01/09/1998
Duration12 months

Abstract

The PufX protein is responsible for organising the proper assembly of the reaction centre/light harvesting complex 1 photosystem in Rhodobacter sphaeroides. Under funding from BBSRC grant 50/C01645, genetic engineering has been used to change the identity of the PufX protein, and to alter the primary sequence of the protein. Steady-state spectroscopy and growth studies have been used to determine the consequences of these changes for assembly of the photosystem. In the present study, the functional consequences of these changes will be examined by measuring the kinetics of light-driven cyclic electron transfer and membrane potential generation using a novel experimental system that consists of photosynthetic membranes that have been fused to liposomes.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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