Award details

TETRASPORE: a gene essential for male meiotic cytokinesis in Arabidopsis

Reference	P08384
Principal Investigator / Supervisor	Professor Hugh Dickinson
Co-Investigators / Co-Supervisors	Professor Roderick Scott
Institution	University of Oxford
Department	Plant Sciences
Funding type	Research
Value (£)	187,542
Status	Completed
Type	Research Grant
Start date	07/01/1998
End date	01/10/2001
Duration	45 months

Abstract

Tetraspore (TES), a gene essential for male meiotic cytokinesis in Arabidopsis, has been identified and characterised. While loci involved in mitotic division have been described, TES is the first Arabidopsis gene known to be required for meiotic cytokinesis. TES has been mapped within 1 cM of a molecular marker on chromosome 3 and will be isolated by positional cloning. TES expression will be explored using in situ hybridisation, reporter constructs, and immunolocalisation. Nine mutant alleles causing partial or total failure of cytokinesis are available. Mutant and wild-type sequences will be compared to determine which regions of TES are vital to its function. This work will add substantially to our understanding of cytokinesis, and the regulation of gene expression during meiosis.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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