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The second chemosensory pathway in Rhodobacter sphaeroides: its interaction with the primary pathway and species distribution

ReferenceP07728
Principal Investigator / Supervisor Professor Judith Armitage
Co-Investigators /
Co-Supervisors
Institution University of Oxford
DepartmentBiochemistry
Funding typeResearch
Value (£) 160,196
StatusCompleted
TypeResearch Grant
Start date 01/11/1997
End date 01/11/2000
Duration36 months

Abstract

(a) Characterise the role of the two CheY response regulator homologues in signalling and signal termination in Rhodobacter sphaeroides by using response kinetics and protein-protein interaction studies. (b) Characterise the second chemosensory pathway, and identify its relationship to the first chemosensory pathway and to metabolic activity, by cloning and characterising the genes of this newly identified pathway and the phenotypes of in-frame mutants. (c) Identify whether having two chemosensory pathways is a common feature of the environmentally important alpha-subgroup of proteo-bacteria by hybridisation, by PCR cloning and by mutagenesis studies on a range of species from this subgroup.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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