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Identification and characterisation of immediate early genes involved in the elaboration of the hypersensitive response in plants
Reference
P07702
Principal Investigator / Supervisor
Professor Murray Grant
Co-Investigators /
Co-Supervisors
Institution
Imperial College London
Department
Biological Sciences
Funding type
Research
Value (£)
154,096
Status
Completed
Type
Research Grant
Start date
01/12/1997
End date
01/12/2000
Duration
36 months
Abstract
The elaboration of the hypersensitive response (HR) results in rapid changes to host cell physiology and metabolism through a highly coordinated programme of cell death. Clearly this process requires intimate cross-talk between pathogen and host, and host cellular communication in the immediate vicinity of pathogen infection. We propose two complementary approaches to identify immediate early genes involved in the HR elaborated by an effective triggering of the RPM1 mediated disease resistance signal transduction pathway (DRSTP); (i) use arbitrary primed PCR fingerprinting of RNA to identify immediate early genes transcriptionally activated/repressed during the DRSTP (ii) identify potential regulatory protein kinases which are post-transcriptionally activated during the DRSTP.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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