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Genetic engineering of controllable salicylate synthesis and systemic immunity in plants
Reference
P07376
Principal Investigator / Supervisor
Professor John Draper
Co-Investigators /
Co-Supervisors
Institution
Aberystwyth University
Department
Inst of Biological, Environ & Rural Sci
Funding type
Research
Value (£)
204,114
Status
Completed
Type
Research Grant
Start date
01/08/1997
End date
31/03/2002
Duration
56 months
Abstract
Systemic Acquired Resistance (SAR) to pathogens is directly correlated with a build up of salicylic acid (SA) in non-infected leaves. SA synthesis depends on benzoic acid and H202 production and is limited to tissue surrounding cells undergoing HR. We will engineer SAR in the absence of avirulent pathogen attack by controlled SA synthesis from chorismate, a constitutively available precursor. A bacterial SA-synthesis pathway will be mimicked by controlled expression of a plant isochorismate synthase gene (that we have recently identified) in conjunction with a 2nd bacterial enzyme which converts isochorismate into SA. SA synthesis and SAR will be monitored in transgenic plants and if successful will allow future modification of SAR in crops.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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