Award details

Antisense RNA technology for validating fungicide targets in plant pathogenic fungi

ReferenceP07087
Principal Investigator / Supervisor Dr C Caten
Co-Investigators /
Co-Supervisors
Professor John Lucas
Institution University of Birmingham
DepartmentSch of Biosciences
Funding typeResearch
Value (£) 195,702
StatusCompleted
TypeResearch Grant
Start date 01/07/1997
End date 31/01/2001
Duration43 months

Abstract

The initial aim of the proposed study is to develop antisense technology for the down- regulation of specific genes in the important phytopathogenic fungus Septoria nodorum. Initial experiments will involve a GUS reporter system and available constitutive promoters to express the antisense sequences, but considerable effort will be devoted to the isolation and adaptation of highly-expressed, host inducible promoters. The vectors and procedures developed will be used to test antisense inhibition as a means of validating fungicide targets, using two established targets. If these trials are successful, the new technology will be used by the industrial partners to validate new commercial targets.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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